Production of b-Defensin Antimicrobial Peptides by the Oral Mucosa and Salivary Glands
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Production of beta-defensin antimicrobial peptides by the oral mucosa and salivary glands.
beta-Defensins are cationic peptides with broad-spectrum antimicrobial activity that are produced by epithelia at mucosal surfaces. Two human beta-defensins, HBD-1 and HBD-2, were discovered in 1995 and 1997, respectively. However, little is known about the expression of HBD-1 or HBD-2 in tissues of the oral cavity and whether these proteins are secreted. In this study, we characterized the exp...
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تاریخ انتشار 1999